Der Journal Club des CVcare findet an jedem ersten Dienstag eines Monats statt. Thema für Januar ist eine Studie zum Zusammenhang von Faktoren des Job-Demand-Control-Models und muskuloskelettalen Beschwerden bzw. Bitte klicken Sie auf den Pfeil um zu unserer Veranstaltung zu gelangen. Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria-related pathways in colorectal cancer Everest-Dass A, Nersisyan S, Maar H, Novosad V, Schröder-Schwarz J, Freytag V, Stuke J, Beine M, Schiecke A, Haider M, Kriegs M, Elakad O, Bohnenberger H, Conradi L, Raygorodskaya M, Krause L, von Itzstein M, Tonevitsky A, Schumacher U, Maltseva D, Wicklein D, Lange T MOL ONCOL. Multimodal image-guided laser ablation system for precise 3D tissue sampling and subsequent analysis of biomolecules for cancer research Hahn J, Moritz M, Walter A, Wieck T, Moustafa A, Mansour W, Harms C, Stenzel P, Heeren J, Haider M, Lange T, Schlüter H Imaging, Manipulation, and Analysis of Biomolecules, Cells, and Tissues XXII. Bellingham, Washington: SPIE. Comparison of ex vivo bioluminescence imaging, Alu-qPCR and histology for the quantification of spontaneous lung and bone metastases in subcutaneous xenograft mouse models Haider M, Freytag V, Krause L, Spethmann T, Gosau T, Beine M, Knies C, Schröder-Schwarz J, Horn M, Riecken K, Lange T CLIN EXP METASTAS. Efficacy of zoledronic acid for the elimination of disseminated tumor cells in a clinically relevant, spontaneously metastatic prostate cancer xenograft model Böckelmann L, Freytag V, Ahlers A, Maar H, Gosau T, Baranowsky A, Schmitz R, Pantel K, Schumacher U, Haider M, Lange T BONE. The chemicals between us: First results of the cluster analyses on anatomy embalming procedures in the German-speaking countries Kerner A, Biedermann U, Bräuer L, Caspers S, Doll S, Engelhardt M, Filler T, Ghebremedhin E, Gundlach S, Hayn-Leichsenring G, Heermann S, Hettwer-Steeger I, Hiepe L, Hirt B, Hirtler L, Hörmann R, Kulisch C, Lange T, Leube R, Meuser A, Müller-Gerbl M, Nassenstein C, Neckel P, Nimtschke U, Paulsen F, Prescher A, Pretterklieber M, Schliwa S, Schmidt K, Schmiedl A, Schomerus C, Schulze-Tanzil G, Schumacher U, Schumann S, Spindler V, Streicher J, Tschernig T, Unverzagt A, Valentiner U, Viebahn C, Wedel T, Weigner J, Weninger W, Westermann J, Weyers I, Waschke J, Hammer N ANAT SCI EDUC. Ex Vivo Model of Neuroblastoma Plasticity Schäfer P, Muhs S, Turnbull L, Garwal P, Maar Ultra Young Small Titts Prostituierte Porn, Yorgan T, Tolosa E, Lange T, Windhorst S CANCERS. Detection of Spontaneous Bone Metastases of Solid Human Tumor Xenografts in Mice Freytag V, Valentiner U, Lange T Kim S Hrsg. New York, NY: Humana Press, Tumor cell E-selectin ligands determine partialefficacy of bortezomib on spontaneous lung metastasis formation of solid human tumors in vivo Lange T, Valentiner U, Wicklein D, Maar H, Labitzky V, Ahlers A, Starzonek S, Genduso S, Staffeldt L, Pahlow C, Dück A, Stürken C, Baranowsky A, Bauer A, Bulk E, Schwab A, Riecken K, Börnchen C, Kiefmann R, Abraham V, DeLisser H, Gemoll T, Habermann J, Block A, Pantel K, Schumacher U MOL THER. Low expression of CD24 is associated with poor survival in colorectal cancer Nersisyan S, Ahlers A, Lange T, Wicklein D, Galatenko A, Bohnenberger H, Elakad O, Conradi L, Genduso S, Maar H, Schiecke A, Maltseva D, Raygorodskaya M, Makarova J, Schumacher U, Tonevitsky A BIOCHIMIE. CHD1 loss negatively influences metastasis-free survival in R0-resected prostate cancer patients and promotes spontaneous metastasis in vivo Oh-Hohenhorst S, Tilki D, Ahlers A, Suling A, Hahn O, Tennstedt P, Matuszcak C, Maar H, Labitzky V, Hanika S, Starzonek S, Baumgart S, Johnsen S, Kluth M, Sirma H, Simon R, Sauter G, Huland H, Schumacher U, Lange T CANCER GENE THER. Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis Wang Ultra Young Small Titts Prostituierte Porn, Liu X, Obser T, Bauer A, Heyes M, Starzonek S, Zulal M, Opitz K, Ott L, Riethdorf S, Lange T, Pantel K, Bendas G, Schneider S, Kusche-Gullberg M, Gorzelanny C MATRIX BIOL. Procalcitonin Exerts a Mediator Role in Septic Shock Through the Calcitonin Gene-Related Peptide Receptor Baranowsky A, Appelt J, Kleber C, Lange T, Ludewig P, Jahn D, Pandey P, Keller D, Rose T, Schetler D, Braumüller S, Huber-Lang M, Tsitsilonis S, Yorgan T, Frosch K, Amling M, Schinke T, Keller J CRIT CARE MED. The Role of Platelet Cell Surface P-Selectin for the Direct Platelet-Tumor Cell Contact During Metastasis Formation in Human Tumors Fabricius H, Starzonek S, Lange T FRONT ONCOL. Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression Kemper M, Schiecke A, Maar H, Nikulin S, Poloznikov A, Galatenko V, Tachezy M, Gebauer F, Lange T, Riecken K, Tonevitsky A, Aigner A, Izbicki J, Schumacher U, Wicklein D J EXP CLIN CANC RES. Role of Metastasis-Related microRNAs in Prostate Cancer Progression and Treatment Oh-Hohenhorst S, Lange T CANCERS. Opposing Ultra Young Small Titts Prostituierte Porn relevance of junction plakoglobin in distinct prostate cancer patient subsets Spethmann T, Böckelmann L, Labitzky V, Ahlers A, Schröder-Schwarz J, Bonk S, Simon R, Sauter G, Huland H, Kypta R, Schumacher U, Lange T MOL ONCOL. The initial engraftment of tumor cells is critical for the future growth pattern: a mathematical study based on simulations and animal experiments Hoffmann B, Lange T, Labitzky V, Riecken K, Wree A, Schumacher U, Wedemann G BMC CANCER. Modeling Spontaneous Bone Metastasis Formation of Solid Human Tumor Xenografts in Mice Labitzky V, Baranowsky A, Maar H, Hanika S, Starzonek S, Ahlers A, Stübke K, Koziolek E, Heine M, Schäfer P, Windhorst S, Jücker M, Riecken K, Amling M, Schinke T, Schumacher U, Valentiner U, Lange T CANCERS. Glioma escape signature and clonal development under immune pressure Maire C, Mohme M, Bockmayr M, Fita K, Riecken K, Börnigen D, Alawi M, Failla A, Kolbe K, Zapf S, Holz M, Neumann K, Dührsen L, Lange T, Fehse B, Westphal M, Lamszus K J CLIN INVEST. Systematic analysis of the human tumor cell binding to human vs. A functional ex vivo assay to detect PARP1-EJ repair and radiosensitization by PARP-inhibitor in prostate cancer Köcher S, Beyer B, Lange T, Nordquist L, Volquardsen J, Burdak-Rothkamm S, Schlomm T, Petersen C, Rothkamm K, Mansour W INT J CANCER. Probennahme per Laserablation von Krebsgeweben für Proteomics Lange T, Schlüter H BIOspektrum. Effect of the actin- and calcium-regulating activities of ITPKB on the metastatic potential of lung cancer cells Bäder S, Glaubke E, Grüb S, Muhs S, Wellbrock J, Nalaskowski M, Lange T, Windhorst S BIOCHEM J. Knockdown of L1CAM significantly reduces metastasis in a xenograft model of human melanoma: L1CAM is a potential target for anti-melanoma therapy Ernst A, Putscher A, Samatov T, Suling A, Galatenko V, Shkurnikov M, Knyazev E, Tonevitsky A, Haalck T, Lange T, Maar H, Schröder-Schwarz J, Riecken K, Schumacher U, Wicklein D PLOS ONE. Locally Ablative Radiation Therapy of a Primary Human Small Cell Lung Cancer Tumor Decreases the Number of Spontaneous Metastases in Two Xenograft Models Frenzel T, Siekmann J, Grohmann C, Valentiner U, Schmitz R, Riecken K, Fehse B, Schumacher U, Lange T, Krüll A INT J RADIAT ONCOL. Differential Proteome Analysis of Human Neuroblastoma Xenograft Primary Tumors and Matched Spontaneous Distant Ultra Young Small Titts Prostituierte Porn Hänel L, Gosau T, Maar H, Valentiner U, Schumacher U, Riecken K, Windhorst S, Hansen N, Heikaus L, Wurlitzer M, Nolte I, Schlüter H, Lange T SCI REP-UK. Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer Lange T, Oh-Hohenhorst S, Joosse S, Pantel K, Hahn O, Gosau T, Dyshlovoy S, Wellbrock J, Feldhaus S, Maar H, Gehrcke R, Kluth M, Simon R, Schlomm T, Huland H, Schumacher U SCI REP-UK. Clinical relevance of cytoskeleton associated proteins for ovarian cancer Schiewek J, Schumacher U, Lange T, Joosse S, Wikman H, Pantel K, Mikhaylova M, Kneussel M, Linder S, Schmalfeldt B, Oliveira-Ferrer L, Windhorst S J CANCER RES CLIN. CEACAM1 promotes melanoma metastasis and is involved in the regulation of the EMT associated gene network in melanoma cells Wicklein D, Otto B, Suling A, Elies E, Lüers G, Lange T, Feldhaus S, Maar H, Schröder-Schwarz J, Brunner G, Wagener C, Schumacher U SCI REP-UK. Downregulation of AKT3 Increases Migration and Metastasis in Triple Negative Breast Cancer Cells by Upregulating SA4 Grottke A, Ewald F, Lange T, Nörz D, Herzberger C, Bach J, Grabinski N, Gräser L, Höppner F, Nashan B, Schumacher U, Jücker M PLOS ONE. Intracellular and extracellular microRNA: An update on localization and biological role Makarova J, Shkurnikov M, Wicklein D, Lange T, Samatov T, Turchinovich A, Tonevitsky A PROG HISTOCHEM CYTO. SDA, a DNA aptamer inhibiting E- and P-selectin mediated adhesion of cancer and leukemia cells, the first and pivotal step in transendothelial migration during metastasis formation Faryammanesh R, Lange T, Magbanua E, Haas S, Meyer C, Wicklein D, Schumacher U, Hahn U PLOS ONE. Aberrant presentation of HPA-reactive carbohydrates implies Selectin-independent metastasis formation in human prostate cancer Lange T, Kupfernagel M, Wicklein D, Gebauer F, Maar H, Brügge K, Müller I, Simon R, Schlomm T, Sauter G, Schumacher U CLIN CANCER RES. Importance of altered glycoprotein-bound N- and O-glycans for epithelial-to-mesenchymal transition and adhesion of cancer cells Lange T, Samatov T, Tonevitsky A, Schumacher U CARBOHYD RES. Expression of DIAPH1 is up-regulated in colorectal cancer and its down-regulation strongly reduces the metastatic capacity of colon carcinoma cells Lin Y, Izbicki J, König A, Habermann J, Blechner C, Lange T, Schumacher U, Windhorst S INT J CANCER. Expression of the coxsackie adenovirus receptor in neuroendocrine lung cancers and its implications for oncolytic adenoviral infection. Wunder T, Schmid K, Wicklein D, Groitl P, Dobner T, Lange T, Anders M, Schumacher U CANCER GENE THER. Divergent resorbability and effects on osteoclast formation of commonly used bone substitutes in a human in vitro-assay.
F Biol Rep. Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats. In permanent atrial fibrillation, PDE3 reduces force responses to 5-HT, but PDE3 and PDE4 do not cause the blunting of atrial arrhythmias Berk E, Christ T, Schwarz S, Ravens U, Knaut M, Kaumann A BRIT J PHARMACOL. THE BIG BOOK OF BREASTS The Golden Age of Natural Curves. A Transgenic Mouse Model of Eccentric Left Ventricular Hypertrophy With Preserved Ejection Fraction Exhibits Alterations in the Autophagy-Lysosomal Pathway Wenzel K, Krämer E, Geertz B, Carrier L, Felix S, Könemann S, Schlossarek S FRONT PHYSIOL.
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